Protein Details: Aquaporin PIP2-7

Protein ID

ICDB_Pro_0714

Protein Name

Aquaporin PIP2-7

Gene Name

PIP2-7; PIP3; SIMIP; At4g35100; M4E13.150

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

280 amino acids

AlphaFoldDB

AF-P93004-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across cell membrane. May be involved in the osmoregulation in plants under high osmotic stress such as under a high salt condition.

Sequence

MSKEVSEEGKTHHGKDYVDPPPAPLLDMGELKSWSFYRALIAEFIATLLFLYVTVATVIGHKKQTGPCDGVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVSLVRALGYMIAQCLGAICGVGFVKAFMKTPYNTLGGGANTVADGYSKGTALGAEIIGTFVLVYTVFSATDPKRSARDSHIPVLAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIYNNEKAWDDQWIFWVGPFLGALAAAAYHQYILRASAIKALGSFRSNATN

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Highly expressed in flowers; expressed at low levels in siliques; and at low level in leaves and roots; Highly levels in elongating cells in both roots and shoots.

DOI ID

10.1104/pp.114.4.1347; 10.1038/47134; 10.1111/tpj.13415; 10.1126/science.1088305; 10.1073/pnas.97.7.3718; 10.1186/gb-2001-3-1-research0001; 10.1074/mcp.m400001-mcp200; 10.1021/pr8000173; 10.1104/pp.109.138677; 10.1105/tpc.114.127159

RefSeq

NP_001190920.1; NP_195236.1